You don't need to use a midi out channel to assign your mod wheel or sliders. That is what you want to do right?
For example, to link a slider (on your controller) to a channel volume: right click on the channel volume knob, select link to controller, then move the slider on your controller. It should link automatically and the link will be saved in the project so every time you open the project the controls will be linked. You can do the same for the mod wheel, knobs, and buttons/ pads and with any parameter in FL or on a VST.
FL responds to midi in omni mode, meaning all channels at once. There is no need to use a midi out to control anything, unless you have a multitimbral synth that uses a different channel for each module. You don't need to send midi out from FL to your MPK49 either (in midi options) I'm not sure if it will cause any trouble.